Expression of maspin in endometrioid adenocarcinoma of endometrium

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Expression of maspin in endometrioid adenocarcinoma of endometrium.

Maspin is a member of the serpin family, whose expression is altered in neoplasia and malignancies of many tissues. Underexpression of maspin has been reported in breast and prostatic cancers, but in some cancers such as ovarian, colorectal and pancreatic carcinoma, it was found to be up-regulated. This study aimed at demonstrating the expression of maspin in human endometrial tissue and search...

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Molecular Analysis of Mixed Endometrioid and Serous Adenocarcinoma of the Endometrium

BACKGROUND The molecular biology and cellular origins of mixed type endometrial carcinomas (MT-ECs) are poorly understood, and a Type II component of 10 percent or less may confer poorer prognoses. METHODOLOGY/PRINCIPAL FINDINGS We studied 10 cases of MT-EC (containing endometrioid and serous differentiation), 5 pure low-grade endometrioid adenocarcinoma (EAC) and 5 pure uterine serous carcin...

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Survival rate of early stage endometrioid adenocarcinoma of endometrium treated at Srinagarind Hospital.

PURPOSE To evaluate the survival outcome of early stage endometrioid adenocarcinoma of the endometrium with risk factors for locoregional recurrence treated with combined pelvic external beam radiotherapy (EBRT) and vaginal brachytherapy (VBT) after comprehensive surgery. MATERIALS AND METHODS Post-operative radiotherapy by pelvic EBRT and VBT for early stage endometrioid endometrial carcinom...

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Polypoid nodular histiocytic hyperplasia associated with endometrioid adenocarcinoma of the endometrium: report of a case

UNLABELLED A 45 year old woman underwent Laparoscopy-assisted total hysterectomy with staging procedure following a diagnosis of endometrial endometrioid adenocarcinoma on her endometrial biopsy. The hysterectomy specimen showed a FIGO I stage 1a, endometrioid carcinoma. A separate polypoid lesion in the endometrium, distinct from the carcinoma, was also identified. Microscopically the polypoid...

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Maspin Gene Expression in Invasive Ductal Carcinoma of Breast

Background: The breast cancer is the most prevalent cancer among women, on the other hand absence of myoepithelial cells play a pivotal role in pathogenesis of this cancer. Thus we aimed to investigate the possible abilities of the molecular assay technique to find a relationship between mammary serine protease inhibitor (Maspin) gene expression possibly secreted by my...

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ژورنال

عنوان ژورنال: Oncology Reports

سال: 2007

ISSN: 1021-335X,1791-2431

DOI: 10.3892/or.17.2.393